Reaction Details Report a problem with these data
Target
Cell division control protein 42 homolog
Ligand
BDBM54698
Substrate
n/a
Meas. Tech.
Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 wildtype
EC50
30000±n/a nM
Citation
 PubChem, PC Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 wildtype PubChem Bioassay (2009)[AID] 
Target
Name:
Cell division control protein 42 homolog
Synonyms:
CDC42 | CDC42_HUMAN | Cell division control protein 42 homolog | G25K GTP-binding protein | cell division cycle 42 (GTP binding protein, 25kDa)
Type:
PROTEIN
Mol. Mass.:
21258.36
Organism:
Homo sapiens (Human)
Description:
ChEMBL_652970
Residue:
191
Sequence:
MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPPEPKKSRRCVLL
  
Inhibitor
Name:
BDBM54698
Synonyms:
3-phenyl-1-(3-pyridinyl)-2-propyn-1-one | 3-phenyl-1-(3-pyridyl)prop-2-yn-1-one | 3-phenyl-1-pyridin-3-yl-prop-2-yn-1-one | 3-phenyl-1-pyridin-3-ylprop-2-yn-1-one | UNM-0000306056 | cid_326117
Type:
Small organic molecule
Emp. Form.:
C14H9NO
Mol. Mass.:
207.2274
SMILES:
O=C(C#Cc1ccccc1)c1cccnc1
Structure:
Search PDB for entries with ligand similarity: