Reaction Details Report a problem with these data
Target
Ras-related protein Rab-7a
Ligand
BDBM54704
Substrate
n/a
Meas. Tech.
Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab7 wildtype
EC50
30000±n/a nM
Citation
 PubChem, PC Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab7 wildtype PubChem Bioassay (2009)[AID] 
Target
Name:
Ras-related protein Rab-7a
Synonyms:
GTP-binding protein (rab7) | RAB7 | RAB7A | RAB7A_CANLF
Type:
Enzyme Catalytic Domain
Mol. Mass.:
23519.50
Organism:
Canis lupus familiaris
Description:
gi_164058
Residue:
207
Sequence:
MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDKNDRAKTSAESCSC
  
Inhibitor
Name:
BDBM54704
Synonyms:
UNM-0000306098 | cid_23681059 | sodium;(2S)-2-(6-methoxy-2-naphthalenyl)propanoate | sodium;(2S)-2-(6-methoxy-2-naphthyl)propionate | sodium;(2S)-2-(6-methoxynaphthalen-2-yl)propanoate
Type:
Small organic molecule
Emp. Form.:
C14H13O3
Mol. Mass.:
229.2518
SMILES:
COc1ccc2cc(ccc2c1)[C@H](C)C([O-])=O
Structure:
Search PDB for entries with ligand similarity: