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Target
Kappa-type opioid receptor
Ligand
BDBM54776
Substrate
n/a
Meas. Tech.
HTS Image-Based Screen for Selective Agonists of the KOR Receptor
EC50
9054.219±n/a nM
Citation
 PubChem, PC HTS Image-Based Screen for Selective Agonists of the KOR Receptor PubChem Bioassay (2009)[AID] 
Target
Name:
Kappa-type opioid receptor
Synonyms:
K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42648.76
Organism:
Homo sapiens (Human)
Description:
P41145
Residue:
380
Sequence:
MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRVRNTVQDPAYLRDIDGMNKPV
  
Inhibitor
Name:
BDBM54776
Synonyms:
MLS000095001 | N-[1-(cyclopentylamino)-2-methyl-1-oxidanylidene-butan-2-yl]-N-(furan-2-ylmethyl)pyridine-2-carboxamide | N-[1-(cyclopentylamino)-2-methyl-1-oxobutan-2-yl]-N-(2-furanylmethyl)-2-pyridinecarboxamide | N-[1-(cyclopentylamino)-2-methyl-1-oxobutan-2-yl]-N-(furan-2-ylmethyl)pyridine-2-carboxamide | N-[1-(cyclopentylcarbamoyl)-1-methyl-propyl]-N-(2-furfuryl)picolinamide | SMR000030552 | cid_3237419
Type:
Small organic molecule
Emp. Form.:
C21H27N3O3
Mol. Mass.:
369.4574
SMILES:
CCC(C)(N(Cc1ccco1)C(=O)c1ccccn1)C(=O)NC1CCCC1
Structure:
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