Reaction Details Report a problem with these data
Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM54790
Substrate
n/a
Meas. Tech.
HTS HePTP Fluorescent Assay using OMFP substrate for In Vitro dose response studies
IC50
99000±0 nM
Citation
 PubChem, PC HTS HePTP Fluorescent Assay using OMFP substrate for In Vitro dose response studies PubChem Bioassay (2009)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM54790
Synonyms:
MLS000698624 | N'-(1,3-benzodioxol-5-ylmethylene)-2-(4-pyridinyl)-4-quinolinecarbohydrazide | N-(1,3-benzodioxol-5-ylmethylideneamino)-2-pyridin-4-yl-4-quinolinecarboxamide | N-(1,3-benzodioxol-5-ylmethylideneamino)-2-pyridin-4-yl-quinoline-4-carboxamide | N-(1,3-benzodioxol-5-ylmethylideneamino)-2-pyridin-4-ylquinoline-4-carboxamide | N-(piperonylideneamino)-2-(4-pyridyl)cinchoninamide | SMR000228182 | cid_999332
Type:
Small organic molecule
Emp. Form.:
C23H16N4O3
Mol. Mass.:
396.3981
SMILES:
O=C(NN=Cc1ccc2OCOc2c1)c1cc(nc2ccccc12)-c1ccncc1
Structure:
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