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Target
2'-phosphotransferase
Ligand
BDBM55011
Substrate
n/a
Meas. Tech.
Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of tRNA 2'-phosphotransferase (TPT1).
IC50
5551±n/a nM
Citation
 PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of tRNA 2'-phosphotransferase (TPT1). PubChem Bioassay (2009)[AID] 
Target
Name:
2'-phosphotransferase
Synonyms:
likely tRNA 2'-phosphotransferase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
23631.37
Organism:
Candida albicans SC5314
Description:
gi_68476498
Residue:
207
Sequence:
MPPPDKARRDVLISKALSYLLRHGAEKEKLSIDDQGYVKISDVLSHQRLKSLKTTRDDINRIVQENDKKRFTIKDDMICANQGHSLKAVKNDNLTPMTVDELNQLRIYHGTYRTKLPLIKSSGGLSKMNRNHIHFTCEQYSTCSGIRYNANVLIYINASKCIEHGIVFYKSLNNVILTSGDKDGKLSWEFIDRIVGLDGNEINKEQV
  
Inhibitor
Name:
BDBM55011
Synonyms:
(5E)-1-(4-methylphenyl)-5-[(5-nitro-2-furanyl)methylidene]-1,3-diazinane-2,4,6-trione | (5E)-1-(4-methylphenyl)-5-[(5-nitro-2-furyl)methylene]pyrimidine-2,4,6(1H,3H,5H)-trione | (5E)-1-(4-methylphenyl)-5-[(5-nitrofuran-2-yl)methylidene]-1,3-diazinane-2,4,6-trione | (5E)-5-[(5-nitro-2-furyl)methylene]-1-(p-tolyl)barbituric acid | MLS000723838 | SMR000305433 | cid_2201932
Type:
Small organic molecule
Emp. Form.:
C16H11N3O6
Mol. Mass.:
341.275
SMILES:
Cc1ccc(cc1)-n1c(=O)[nH]c([O-])c([CH+]c2ccc(o2)[N+]([O-])=O)c1=O
Structure:
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