Reaction Details Report a problem with these data
Target
2'-phosphotransferase
Ligand
BDBM51782
Substrate
n/a
Meas. Tech.
Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of tRNA 2'-phosphotransferase (TPT1).
IC50
2439±n/a nM
Citation
 PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of tRNA 2'-phosphotransferase (TPT1). PubChem Bioassay (2009)[AID] 
Target
Name:
2'-phosphotransferase
Synonyms:
likely tRNA 2'-phosphotransferase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
23631.37
Organism:
Candida albicans SC5314
Description:
gi_68476498
Residue:
207
Sequence:
MPPPDKARRDVLISKALSYLLRHGAEKEKLSIDDQGYVKISDVLSHQRLKSLKTTRDDINRIVQENDKKRFTIKDDMICANQGHSLKAVKNDNLTPMTVDELNQLRIYHGTYRTKLPLIKSSGGLSKMNRNHIHFTCEQYSTCSGIRYNANVLIYINASKCIEHGIVFYKSLNNVILTSGDKDGKLSWEFIDRIVGLDGNEINKEQV
  
Inhibitor
Name:
BDBM51782
Synonyms:
(5E)-5-(2-furanylmethylidene)-1-(2-methylphenyl)-2-sulfanylidene-1,3-diazinane-4,6-dione | (5E)-5-(2-furfurylidene)-1-(o-tolyl)-2-thioxo-hexahydropyrimidine-4,6-quinone | (5E)-5-(furan-2-ylmethylidene)-1-(2-methylphenyl)-2-sulfanylidene-1,3-diazinane-4,6-dione | MLS001163797 | SMR000539168 | cid_1557339
Type:
Small organic molecule
Emp. Form.:
C16H12N2O3S
Mol. Mass.:
312.343
SMILES:
Cc1ccccc1N1C(=S)NC(=O)C(=Cc2ccco2)C1=O |w:14.15|
Structure:
Search PDB for entries with ligand similarity: