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Target
2'-phosphotransferase
Ligand
BDBM51791
Substrate
n/a
Meas. Tech.
Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of tRNA 2'-phosphotransferase (TPT1).
IC50
3548±n/a nM
Citation
 PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of tRNA 2'-phosphotransferase (TPT1). PubChem Bioassay (2009)[AID] 
Target
Name:
2'-phosphotransferase
Synonyms:
likely tRNA 2'-phosphotransferase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
23631.37
Organism:
Candida albicans SC5314
Description:
gi_68476498
Residue:
207
Sequence:
MPPPDKARRDVLISKALSYLLRHGAEKEKLSIDDQGYVKISDVLSHQRLKSLKTTRDDINRIVQENDKKRFTIKDDMICANQGHSLKAVKNDNLTPMTVDELNQLRIYHGTYRTKLPLIKSSGGLSKMNRNHIHFTCEQYSTCSGIRYNANVLIYINASKCIEHGIVFYKSLNNVILTSGDKDGKLSWEFIDRIVGLDGNEINKEQV
  
Inhibitor
Name:
BDBM51791
Synonyms:
5-[(3,5-dimethyl-1-pyrazolyl)methyl]-N-[[5-(4-nitrophenyl)-2-furanyl]methylideneamino]-2-furancarboxamide | 5-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]-N'-[(5-{4-nitrophenyl}-2-furyl)methylene]-2-furohydrazide | 5-[(3,5-dimethylpyrazol-1-yl)methyl]-N-[[5-(4-nitrophenyl)-2-furyl]methyleneamino]-2-furamide | 5-[(3,5-dimethylpyrazol-1-yl)methyl]-N-[[5-(4-nitrophenyl)furan-2-yl]methylideneamino]furan-2-carboxamide | MLS001240080 | SMR000673320 | cid_1000028
Type:
Small organic molecule
Emp. Form.:
C22H19N5O5
Mol. Mass.:
433.4168
SMILES:
Cc1cc(C)n(Cc2ccc(o2)C(=O)N\N=C\c2ccc(o2)-c2ccc(cc2)[N+]([O-])=O)n1
Structure:
Search PDB for entries with ligand similarity: