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Target
M18 aspartyl aminopeptidase
Ligand
BDBM55128
Substrate
n/a
Meas. Tech.
QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PFM18AAP).
IC50
831.99±n/a nM
Citation
 PubChem, PC QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PFM18AAP). PubChem Bioassay (2009)[AID] 
Target
Name:
M18 aspartyl aminopeptidase
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
65642.43
Organism:
Plasmodium falciparum 3D7
Description:
gi_23505220
Residue:
570
Sequence:
MDKKAREYAQDALKFIQRSGSNFLACKNLKERLENNGFINLSEGETWNLNKNEGYVLCKENRNICGFFVGKNFNIDTGSILISIGHIDSCALKISPNNNVIKKKIHQINVECYGSGLWHTWFDRSLGLSGQVLYKKGNKLVEKLIQINKSVLFLPSLAIHLQNRTRYDFSVKINYENHIKPIISTTLFNQLNKCKRNNVHHDTILTTDTKFSHKENSQNKRDDQMCHSFNDKDVSNHNLDKNTIEHLTNQQNEEKNKHTKDNPNSKDIVEHINTDNSYPLLYLLSKELNCKEEDILDFELCLMDTQEPCFTGVYEEFIEGARFDNLLGSFCVFEGFIELVNSIKNHTSNENTNHTNNITNDINDNIHNNLYISIGYDHEEIGSLSEVGARSYCTKNFIDRIISSVFKKEIHEKNLSVQEIYGNLVNRSFILNVDMAHCSHPNYPETVQDNHQLFFHEGIAIKYNTNKNYVTSPLHASLIKRTFELYYNKYKQQIKYQNFMVKNDTPCGSTVGSMVAANLSMPGIDIGIPQLAMHSIREIAAVHDVFFLIKGVFAFYTYYNQVLSTCVHDK
  
Inhibitor
Name:
BDBM55128
Synonyms:
1-(5-chloranyl-2-methoxy-phenyl)-3-(1,2,4-triazol-4-yl)urea | 1-(5-chloro-2-methoxy-phenyl)-3-(1,2,4-triazol-4-yl)urea | 1-(5-chloro-2-methoxyphenyl)-3-(1,2,4-triazol-4-yl)urea | MLS000537637 | N-(5-chloro-2-methoxyphenyl)-N'-4H-1,2,4-triazol-4-ylurea | SMR000143879 | cid_971074
Type:
Small organic molecule
Emp. Form.:
C10H10ClN5O2
Mol. Mass.:
267.672
SMILES:
COc1ccc(Cl)cc1NC(=O)Nn1cnnc1
Structure:
Search PDB for entries with ligand similarity: