Reaction Details Report a problem with these data
Target
Kallikrein-5
Ligand
BDBM32791
Substrate
n/a
Meas. Tech.
Kallikrein 5 1536 HTS Dose Response Confirmation
IC50
1092.57±n/a nM
Citation
 PubChem, PC Kallikrein 5 1536 HTS Dose Response Confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Kallikrein-5
Synonyms:
KLK5 | KLK5_HUMAN | Kallikrein 5 | SCTE | kallikrein-related peptidase 5 preproprotein
Type:
PROTEIN
Mol. Mass.:
32031.72
Organism:
Homo sapiens (Human)
Description:
EBI_12584
Residue:
293
Sequence:
MATARPPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS
  
Inhibitor
Name:
BDBM32791
Synonyms:
1-(1-benzothien-3-ylcarbonyl)-1H-pyrazole | 1-benzothiophen-3-yl(1-pyrazolyl)methanone | 1-benzothiophen-3-yl(pyrazol-1-yl)methanone | MLS000065687 | SMR000080341 | benzothiophen-3-yl(pyrazol-1-yl)methanone | cid_841465
Type:
Small organic molecule
Emp. Form.:
C12H8N2OS
Mol. Mass.:
228.27
SMILES:
O=C(c1csc2ccccc12)n1cccn1
Structure:
Search PDB for entries with ligand similarity: