Reaction Details Report a problem with these data
Target
DNA repair protein RAD51 homolog 1
Ligand
BDBM56841
Substrate
n/a
Meas. Tech.
Homologous Recombination - Rad 51_Dose response
IC50
42500±n/a nM
Citation
 PubChem, PC Homologous Recombination - Rad 51_Dose response PubChem Bioassay (2008)[AID] 
Target
Name:
DNA repair protein RAD51 homolog 1
Synonyms:
RAD51 | RAD51A | RAD51_HUMAN | RECA
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36960.74
Organism:
Homo sapiens (Human)
Description:
gi_49168602
Residue:
339
Sequence:
MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD
  
Inhibitor
Name:
BDBM56841
Synonyms:
4-[2-[[2-[(3-methyl-1,3-benzothiazol-2-ylidene)amino]-2-oxoethyl]thio]-1-oxoethyl]-1-piperazinecarboxylic acid ethyl ester | 4-[2-[[2-keto-2-[(3-methyl-1,3-benzothiazol-2-ylidene)amino]ethyl]thio]acetyl]piperazine-1-carboxylic acid ethyl ester | MLS000091398 | SMR000025954 | cid_3237774 | ethyl 4-[2-[2-[(3-methyl-1,3-benzothiazol-2-ylidene)amino]-2-oxidanylidene-ethyl]sulfanylethanoyl]piperazine-1-carboxylate | ethyl 4-[2-[2-[(3-methyl-1,3-benzothiazol-2-ylidene)amino]-2-oxoethyl]sulfanylacetyl]piperazine-1-carboxylate | ethyl 4-{[(2-{[(2Z)-3-methyl-1,3-benzothiazol-2(3H)-ylidene]amino}-2-oxoethyl)thio]acetyl}piperazine-1-carboxylate
Type:
Small organic molecule
Emp. Form.:
C19H24N4O4S2
Mol. Mass.:
436.548
SMILES:
CCOC(=O)N1CCN(CC1)C(=O)CSCC(=O)N=c1sc2ccccc2n1C |w:18.18|
Structure:
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