Reaction Details Report a problem with these data
Target
DNA repair protein RAD51 homolog 1
Ligand
BDBM43831
Substrate
n/a
Meas. Tech.
Homologous Recombination - Rad 51_Dose response
IC50
42500±n/a nM
Citation
 PubChem, PC Homologous Recombination - Rad 51_Dose response PubChem Bioassay (2008)[AID] 
Target
Name:
DNA repair protein RAD51 homolog 1
Synonyms:
RAD51 | RAD51A | RAD51_HUMAN | RECA
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36960.74
Organism:
Homo sapiens (Human)
Description:
gi_49168602
Residue:
339
Sequence:
MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD
  
Inhibitor
Name:
BDBM43831
Synonyms:
5-(4-fluorobenzyl)-4-keto-6,7-dihydropyrazolo[1,5-a]pyrazine-2-carboxylic acid methyl ester | 5-[(4-fluorophenyl)methyl]-4-oxo-6,7-dihydropyrazolo[1,5-a]pyrazine-2-carboxylic acid methyl ester | Glucosamine derivative, 4 | MLS000326913 | SMR000179467 | cid_1475682 | methyl 5-(4-fluorobenzyl)-4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxylate | methyl 5-[(4-fluorophenyl)methyl]-4-oxidanylidene-6,7-dihydropyrazolo[1,5-a]pyrazine-2-carboxylate | methyl 5-[(4-fluorophenyl)methyl]-4-oxo-6,7-dihydropyrazolo[1,5-a]pyrazine-2-carboxylate
Type:
Small organic molecule
Emp. Form.:
C15H14FN3O3
Mol. Mass.:
303.2884
SMILES:
COC(=O)c1cc2C(=O)N(Cc3ccc(F)cc3)CCn2n1
Structure:
Search PDB for entries with ligand similarity: