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Target
Streptokinase A
Ligand
BDBM38921
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression
EC50
150000±n/a nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM38921
Synonyms:
MLS000056851 | N-(5-ethylsulfanyl-1,3,4-thiadiazol-2-yl)pyridine-2-carboxamide | N-[5-(ethylthio)-1,3,4-thiadiazol-2-yl]-2-pyridinecarboxamide | N-[5-(ethylthio)-1,3,4-thiadiazol-2-yl]picolinamide | SMR000067448 | cid_2121806
Type:
Small organic molecule
Emp. Form.:
C10H10N4OS2
Mol. Mass.:
266.343
SMILES:
CCSc1nnc(NC(=O)c2ccccn2)s1
Structure:
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