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Target
Streptokinase A
Ligand
BDBM57726
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression
EC50
150000±n/a nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM57726
Synonyms:
(2Z)-2-(4-chlorophenyl)sulfonyl-2-(phenylhydrazono)acetohydrazide | 2-(4-chlorophenyl)sulfonyl-2-(phenylhydrazinylidene)acetohydrazide | 2-(4-chlorophenyl)sulfonyl-2-(phenylhydrazinylidene)ethanehydrazide | 2-(4-chlorophenyl)sulfonyl-2-(phenylhydrazono)acetohydrazide | 2-[(4-chlorophenyl)sulfonyl]-2-(phenylhydrazono)acetohydrazide | MLS000700702 | SMR000225122 | cid_1210927
Type:
Small organic molecule
Emp. Form.:
C14H13ClN4O3S
Mol. Mass.:
352.796
SMILES:
NNC(=O)C(=NNc1ccccc1)S(=O)(=O)c1ccc(Cl)cc1 |w:5.5|
Structure:
Search PDB for entries with ligand similarity: