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Target
Streptokinase A
Ligand
BDBM58088
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression
EC50
150000±n/a nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM58088
Synonyms:
(6Z)-6-[5-(4-chlorophenyl)-3-pyrazolidinylidene]-4-methyl-1-cyclohexa-2,4-dienone | (6Z)-6-[5-(4-chlorophenyl)pyrazolidin-3-ylidene]-4-methyl-cyclohexa-2,4-dien-1-one | (6Z)-6-[5-(4-chlorophenyl)pyrazolidin-3-ylidene]-4-methylcyclohexa-2,4-dien-1-one | 2-[5-(4-Chloro-phenyl)-4,5-dihydro-1H-pyrazol-3-yl]-4-methyl-phenol | MLS000807012 | SMR000414826 | cid_5904485
Type:
Small organic molecule
Emp. Form.:
C16H15ClN2O
Mol. Mass.:
286.756
SMILES:
Cc1ccc(O)c(c1)C1CC(N=N1)c1ccc(Cl)cc1 |c:12|
Structure:
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