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Target
Streptokinase A
Ligand
BDBM58096
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression
EC50
31070±n/a nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM58096
Synonyms:
1-[4-(4-chlorophenyl)-1-piperazinyl]-3-(1-naphthalenyloxy)-2-propanol | 1-[4-(4-chlorophenyl)piperazin-1-yl]-3-naphthalen-1-yloxy-propan-2-ol | 1-[4-(4-chlorophenyl)piperazin-1-yl]-3-naphthalen-1-yloxypropan-2-ol | 1-[4-(4-chlorophenyl)piperazino]-3-(1-naphthoxy)propan-2-ol | MLS000737719 | SMR000528427 | cid_260309
Type:
Small organic molecule
Emp. Form.:
C23H25ClN2O2
Mol. Mass.:
396.91
SMILES:
OC(COc1cccc2ccccc12)CN1CCN(CC1)c1ccc(Cl)cc1
Structure:
Search PDB for entries with ligand similarity: