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Target
Streptokinase A
Ligand
BDBM58117
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression
EC50
150000±n/a nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM58117
Synonyms:
1-(2-Hydroxy-ethylamino)-9,10-dioxo-9,10-dihydro-anthracene-2-carboxylic acid (2-diethylamino-ethyl)-amide | MLS000770002 | N-[2-(diethylamino)ethyl]-1-(2-hydroxyethylamino)-9,10-bis(oxidanylidene)anthracene-2-carboxamide | N-[2-(diethylamino)ethyl]-1-(2-hydroxyethylamino)-9,10-diketo-anthracene-2-carboxamide | N-[2-(diethylamino)ethyl]-1-(2-hydroxyethylamino)-9,10-dioxo-2-anthracenecarboxamide | N-[2-(diethylamino)ethyl]-1-(2-hydroxyethylamino)-9,10-dioxoanthracene-2-carboxamide | SMR000434735 | cid_3737083
Type:
Small organic molecule
Emp. Form.:
C23H27N3O4
Mol. Mass.:
409.4782
SMILES:
CCN(CC)CCNC(=O)c1ccc2C(=O)c3ccccc3C(=O)c2c1NCCO
Structure:
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