Reaction Details Report a problem with these data
Target
Alkaline phosphatase, germ cell type
Ligand
BDBM39609
Substrate
n/a
Meas. Tech.
Luminescent assay for HTS discovery of chemical activators of placental alkaline phosphatase
EC50
999000±n/a nM
Citation
 PubChem, PC Luminescent assay for HTS discovery of chemical activators of placental alkaline phosphatase PubChem Bioassay (2007)[AID] 
Target
Name:
Alkaline phosphatase, germ cell type
Synonyms:
ALPG | ALPPL | ALPPL2 | Alkaline phosphatase placental-like | PPBN_HUMAN | placental-like alkaline phosphatase preproprotein
Type:
PROTEIN
Mol. Mass.:
57374.31
Organism:
Homo sapiens (Human)
Description:
ChEMBL_29964
Residue:
532
Sequence:
MQGPWVLLLLGLRLQLSLGIIPVEEENPDFWNRQAAEALGAAKKLQPAQTAAKNLIIFLGDGMGVSTVTAARILKGQKKDKLGPETFLAMDRFPYVALSKTYSVDKHVPDSGATATAYLCGVKGNFQTIGLSAAARFNQCNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGAYAHTVNRNWYSDADVPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPDDYSQGGTRLDGKNLVQEWLAKHQGARYVWNRTELLQASLDPSVTHLMGLFEPGDMKYEIHRDSTLDPSLMEMTEAALLLLSRNPRGFFLFVEGGRIDHGHHESRAYRALTETIMFDDAIERAGQLTSEEDTLSLVTADHSHVFSFGGYPLRGSSIFGLAPGKARDRKAYTVLLYGNGPGYVLKDGARPDVTESESGSPEYRQQSAVPLDGETHAGEDVAVFARGPQAHLVHGVQEQTFIAHVMAFAACLEPYTACDLAPRAGTTDAAHPGPSVVPALLPLLAGTLLLLGTATAP
  
Inhibitor
Name:
BDBM39609
Synonyms:
4-[1-(2,4-dimethylphenyl)-2,5-dimethyl-3-pyrrolyl]-4,10-dihydro-[1,3,5]triazino[1,2-a]benzimidazol-2-amine | 4-[1-(2,4-dimethylphenyl)-2,5-dimethyl-pyrrol-3-yl]-4,10-dihydro-[1,3,5]triazino[1,2-a]benzimidazol-2-amine | 4-[1-(2,4-dimethylphenyl)-2,5-dimethylpyrrol-3-yl]-4,10-dihydro-[1,3,5]triazino[1,2-a]benzimidazol-2-amine | MLS000054838 | SMR000060332 | [4-[1-(2,4-dimethylphenyl)-2,5-dimethyl-pyrrol-3-yl]-4,10-dihydro-[1,3,5]triazino[1,2-a]benzimidazol-2-yl]amine | cid_5742556
Type:
Small organic molecule
Emp. Form.:
C23H24N6
Mol. Mass.:
384.4769
SMILES:
Cc1cc(C2N=C(N)Nc3nc4ccccc4n23)c(C)n1-c1ccc(C)cc1C |t:5,(5.56,-1.7,;6.82,-.81,;6.83,.73,;8.3,1.19,;8.8,2.65,;10.37,2.97,;10.86,4.5,;12.37,4.82,;9.78,5.68,;8.22,5.32,;6.97,6.23,;5.73,5.32,;4.16,5.68,;3.08,4.5,;3.58,2.97,;5.15,2.65,;6.2,3.86,;7.74,3.86,;9.19,-.07,;10.73,-.08,;8.28,-1.3,;8.73,-2.77,;10.24,-3.11,;10.7,-4.58,;9.65,-5.71,;10.11,-7.18,;8.15,-5.37,;7.69,-3.9,;6.19,-3.57,)|
Structure:
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