Reaction Details Report a problem with these data
Target
Alkaline phosphatase, germ cell type
Ligand
BDBM39747
Substrate
n/a
Meas. Tech.
Luminescent assay for HTS discovery of chemical activators of placental alkaline phosphatase
EC50
999000±n/a nM
Citation
 PubChem, PC Luminescent assay for HTS discovery of chemical activators of placental alkaline phosphatase PubChem Bioassay (2007)[AID] 
Target
Name:
Alkaline phosphatase, germ cell type
Synonyms:
ALPG | ALPPL | ALPPL2 | Alkaline phosphatase placental-like | PPBN_HUMAN | placental-like alkaline phosphatase preproprotein
Type:
PROTEIN
Mol. Mass.:
57374.31
Organism:
Homo sapiens (Human)
Description:
ChEMBL_29964
Residue:
532
Sequence:
MQGPWVLLLLGLRLQLSLGIIPVEEENPDFWNRQAAEALGAAKKLQPAQTAAKNLIIFLGDGMGVSTVTAARILKGQKKDKLGPETFLAMDRFPYVALSKTYSVDKHVPDSGATATAYLCGVKGNFQTIGLSAAARFNQCNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGAYAHTVNRNWYSDADVPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPDDYSQGGTRLDGKNLVQEWLAKHQGARYVWNRTELLQASLDPSVTHLMGLFEPGDMKYEIHRDSTLDPSLMEMTEAALLLLSRNPRGFFLFVEGGRIDHGHHESRAYRALTETIMFDDAIERAGQLTSEEDTLSLVTADHSHVFSFGGYPLRGSSIFGLAPGKARDRKAYTVLLYGNGPGYVLKDGARPDVTESESGSPEYRQQSAVPLDGETHAGEDVAVFARGPQAHLVHGVQEQTFIAHVMAFAACLEPYTACDLAPRAGTTDAAHPGPSVVPALLPLLAGTLLLLGTATAP
  
Inhibitor
Name:
BDBM39747
Synonyms:
1-benzyl-N'-[(1-ethyl-3,5-dimethyl-1H-pyrazol-4-yl)methylene]-2,3-dimethyl-1H-indole-5-carbohydrazide | 1-benzyl-N-[(1-ethyl-3,5-dimethyl-pyrazol-4-yl)methyleneamino]-2,3-dimethyl-indole-5-carboxamide | 1-benzyl-N-[(1-ethyl-3,5-dimethylpyrazol-4-yl)methylideneamino]-2,3-dimethylindole-5-carboxamide | 1-benzyl-N-[(E)-(1-ethyl-3,5-dimethyl-pyrazol-4-yl)methyleneamino]-2,3-dimethyl-indole-5-carboxamide | MLS000537139 | N-[(1-ethyl-3,5-dimethyl-4-pyrazolyl)methylideneamino]-2,3-dimethyl-1-(phenylmethyl)-5-indolecarboxamide | N-[(1-ethyl-3,5-dimethyl-pyrazol-4-yl)methylideneamino]-2,3-dimethyl-1-(phenylmethyl)indole-5-carboxamide | SMR000159906 | cid_1227745
Type:
Small organic molecule
Emp. Form.:
C26H29N5O
Mol. Mass.:
427.5414
SMILES:
CCn1nc(C)c(C=NNC(=O)c2ccc3n(Cc4ccccc4)c(C)c(C)c3c2)c1C |w:8.8|
Structure:
Search PDB for entries with ligand similarity: