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Target
E3 ubiquitin-protein ligase XIAP
Ligand
BDBM59357
Substrate
n/a
Meas. Tech.
Chemical Antagonists IAP-family anti-apoptotic proteins
IC50
100000±n/a nM
Citation
 PubChem, PC Chemical Antagonists IAP-family anti-apoptotic proteins PubChem Bioassay (2008)[AID] 
Target
Name:
E3 ubiquitin-protein ligase XIAP
Synonyms:
API3 | BIRC4 | E3 ubiquitin-protein ligase XIAP | IAP3 | Inhibitor of apoptosis protein 3 | Inhibitor of apoptosis protein 3 (XIAP) | X-linked inhibitor of apoptosis | X-linked inhibitor of apoptosis protein (XIAP) | XIAP | XIAP_HUMAN
Type:
Protein
Mol. Mass.:
56685.27
Organism:
Homo sapiens (Human)
Description:
P98170
Residue:
497
Sequence:
MTFNSFEGSKTCVPADINKEEEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTTEKTPSLTRRIDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVADLVNAQKDSMQDESSQTSLQKEISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFKQKIFMS
  
Inhibitor
Name:
BDBM59357
Synonyms:
4-[(4,7-dimethyl-2-oxidanylidene-chromen-6-yl)amino]-4-oxidanylidene-butanoic acid | 4-[(4,7-dimethyl-2-oxo-1-benzopyran-6-yl)amino]-4-oxobutanoic acid | 4-[(4,7-dimethyl-2-oxo-2H-chromen-6-yl)amino]-4-oxobutanoic acid | 4-[(4,7-dimethyl-2-oxochromen-6-yl)amino]-4-oxobutanoic acid | 4-keto-4-[(2-keto-4,7-dimethyl-chromen-6-yl)amino]butyric acid | MLS000089643 | SMR000024261 | cid_875166
Type:
Small organic molecule
Emp. Form.:
C15H15NO5
Mol. Mass.:
289.2833
SMILES:
Cc1cc2oc(=O)cc(C)c2cc1NC(=O)CCC(O)=O
Structure:
Search PDB for entries with ligand similarity: