Reaction Details Report a problem with these data
Target
M17 leucyl aminopeptidase
Ligand
BDBM59824
Substrate
n/a
Meas. Tech.
Inhibitors of Plasmodium falciparum M17- Family Leucine Aminopeptidase (M17LAP)
IC50
3220±n/a nM
Citation
 PubChem, PC Inhibitors of Plasmodium falciparum M17- Family Leucine Aminopeptidase (M17LAP) PubChem Bioassay (2009)[AID] 
Target
Name:
M17 leucyl aminopeptidase
Synonyms:
leucine aminopeptidase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
67834.32
Organism:
Plasmodium falciparum 3D7
Description:
gi_124809582
Residue:
605
Sequence:
MYFSSLCKFLPISEKEKIYLNIVKKRFCKSNIYYNNNNNNIINYNKRGLKFYPFCNNLKKNINFVNINNKKGINFHSINKERKMASEVPQVVSLDPTSIPIEYNTPIHDIKVQVYDIKGGCNVEEGLTIFLVNNPGKENGPVKISSKVNDKNVSEFLKDENMEKFNVKLGTSKHFYMFNDNKNSVAVGYVGCGSVADLSEADMKRVVLSLVTMLHDNKLSKLTVVFEINVDKNLFRFFLETLFYEYMTDERFKSTDKNVNMEYIKHLGVYINNADTYKEEVEKARVYYFGTYYASQLIAAPSNYCNPVSLSNAAVELAQKLNLEYKILGVKELEELKMGAYLSVGKGSMYPNKFIHLTYKSKGDVKKKIALVGKGITFDSGGYNLKAAPGSMIDLMKFDMSGCAAVLGCAYCVGTLKPENVEIHFLSAVCENMVSKNSYRPGDIITASNGKTIEVGNTDAEGRLTLADALVYAEKLGVDYIVDIATLTGAMLYSLGTSYAGVFGNNEELINKILNSSKTSNEPVWWLPIINEYRATLNSKYADINNISSSVKASSIVASLFLKEFVQNTAWAHIDIAGVSWNFKARKPKGFGVRLLTEFVLNDAL
  
Inhibitor
Name:
BDBM59824
Synonyms:
1-(4-ethoxyphenyl)-3-thiophen-2-yl-urea | 1-(4-ethoxyphenyl)-3-thiophen-2-ylurea | 1-p-phenetyl-3-(2-thienyl)urea | MLS000520526 | SMR000130937 | cid_9550724
Type:
Small organic molecule
Emp. Form.:
C13H14N2O2S
Mol. Mass.:
262.327
SMILES:
CCOc1ccc(NC(=O)Nc2cccs2)cc1
Structure:
Search PDB for entries with ligand similarity: