Reaction Details Report a problem with these data
Target
M17 leucyl aminopeptidase
Ligand
BDBM59887
Substrate
n/a
Meas. Tech.
Inhibitors of Plasmodium falciparum M17- Family Leucine Aminopeptidase (M17LAP)
IC50
13160±n/a nM
Citation
 PubChem, PC Inhibitors of Plasmodium falciparum M17- Family Leucine Aminopeptidase (M17LAP) PubChem Bioassay (2009)[AID] 
Target
Name:
M17 leucyl aminopeptidase
Synonyms:
leucine aminopeptidase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
67834.32
Organism:
Plasmodium falciparum 3D7
Description:
gi_124809582
Residue:
605
Sequence:
MYFSSLCKFLPISEKEKIYLNIVKKRFCKSNIYYNNNNNNIINYNKRGLKFYPFCNNLKKNINFVNINNKKGINFHSINKERKMASEVPQVVSLDPTSIPIEYNTPIHDIKVQVYDIKGGCNVEEGLTIFLVNNPGKENGPVKISSKVNDKNVSEFLKDENMEKFNVKLGTSKHFYMFNDNKNSVAVGYVGCGSVADLSEADMKRVVLSLVTMLHDNKLSKLTVVFEINVDKNLFRFFLETLFYEYMTDERFKSTDKNVNMEYIKHLGVYINNADTYKEEVEKARVYYFGTYYASQLIAAPSNYCNPVSLSNAAVELAQKLNLEYKILGVKELEELKMGAYLSVGKGSMYPNKFIHLTYKSKGDVKKKIALVGKGITFDSGGYNLKAAPGSMIDLMKFDMSGCAAVLGCAYCVGTLKPENVEIHFLSAVCENMVSKNSYRPGDIITASNGKTIEVGNTDAEGRLTLADALVYAEKLGVDYIVDIATLTGAMLYSLGTSYAGVFGNNEELINKILNSSKTSNEPVWWLPIINEYRATLNSKYADINNISSSVKASSIVASLFLKEFVQNTAWAHIDIAGVSWNFKARKPKGFGVRLLTEFVLNDAL
  
Inhibitor
Name:
BDBM59887
Synonyms:
4-[4-[(3,4-dimethylbenzoyl)amino]phenoxy]phthalic acid | 4-[4-[(3,4-dimethylphenyl)carbonylamino]phenoxy]phthalic acid | 4-[4-[[(3,4-dimethylphenyl)-oxomethyl]amino]phenoxy]phthalic acid | 4-{4-[(3,4-dimethylbenzoyl)amino]phenoxy}phthalic acid | MLS000540821 | SMR000162446 | cid_1026516
Type:
Small organic molecule
Emp. Form.:
C23H19NO6
Mol. Mass.:
405.4001
SMILES:
Cc1ccc(cc1C)C(=O)Nc1ccc(Oc2ccc(C(O)=O)c(c2)C(O)=O)cc1
Structure:
Search PDB for entries with ligand similarity: