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Target
Kappa-type opioid receptor
Ligand
BDBM44525
Substrate
n/a
Meas. Tech.
uHTS identification of small molecule antagonists of the kappa opioid receptor via a luminescent beta-arrestin assay
IC50
2320±n/a nM
Citation
 PubChem, PC uHTS identification of small molecule antagonists of the kappa opioid receptor via a luminescent beta-arrestin assay PubChem Bioassay (2009)[AID] 
Target
Name:
Kappa-type opioid receptor
Synonyms:
K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42648.76
Organism:
Homo sapiens (Human)
Description:
P41145
Residue:
380
Sequence:
MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRVRNTVQDPAYLRDIDGMNKPV
  
Inhibitor
Name:
BDBM44525
Synonyms:
(2E)-2-(2-pyridinylhydrazinylidene)-1-naphthalenone | (2E)-2-(2-pyridylhydrazono)naphthalen-1-one | (2E)-2-(pyridin-2-ylhydrazinylidene)naphthalen-1-one | 2-(2-pyridinyldiazenyl)-1-naphthol | MLS000573813 | SMR000184665 | cid_5718138
Type:
Small organic molecule
Emp. Form.:
C15H11N3O
Mol. Mass.:
249.2673
SMILES:
Oc1c(ccc2ccccc12)N=Nc1ccccn1 |w:11.12|
Structure:
Search PDB for entries with ligand similarity: