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Target
Kappa-type opioid receptor
Ligand
BDBM54826
Substrate
n/a
Meas. Tech.
uHTS identification of small molecule antagonists of the kappa opioid receptor via a luminescent beta-arrestin assay
IC50
10030±n/a nM
Citation
 PubChem, PC uHTS identification of small molecule antagonists of the kappa opioid receptor via a luminescent beta-arrestin assay PubChem Bioassay (2009)[AID] 
Target
Name:
Kappa-type opioid receptor
Synonyms:
K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42648.76
Organism:
Homo sapiens (Human)
Description:
P41145
Residue:
380
Sequence:
MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRVRNTVQDPAYLRDIDGMNKPV
  
Inhibitor
Name:
BDBM54826
Synonyms:
MLS000728493 | Neokadsuranin | SMR000445700 | cid_16745509
Type:
Small organic molecule
Emp. Form.:
C23H26O7
Mol. Mass.:
414.4483
SMILES:
[H]C12OC([H])([C@@H](C)[C@H]1C)c1cc(OC)c(OC)c(OC)c1-c1c(OC)c3OCOc3cc21 |TLB:10:9:2:7.5,17:20:2:7.5,6:5:2:31.9.21.20,THB:30:31:2:7.5,22:21:2:7.5,8:7:2:31.9.21.20|
Structure:
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