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Target
Large T antigen
Ligand
BDBM60363
Substrate
n/a
Meas. Tech.
Identification of SV40 T antigen inhibitors: A route to novel anti-viral reagents
IC50
4830±n/a nM
Citation
 PubChem, PC Identification of SV40 T antigen inhibitors: A route to novel anti-viral reagents PubChem Bioassay (2010)[AID] 
Target
Name:
Large T antigen
Synonyms:
LT | LT-AG | LT_SV40
Type:
Enzyme Catalytic Domain
Mol. Mass.:
81575.54
Organism:
Simian virus 40
Description:
P03070
Residue:
708
Sequence:
MDKVLNREESLQLMDLLGLERSAWGNIPLMRKAYLKKCKEFHPDKGGDEEKMKKMNTLYKKMEDGVKYAHQPDFGGFWDATEIPTYGTDEWEQWWNAFNEENLFCSEEMPSSDDEATADSQHSTPPKKKRKVEDPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYSVTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLCTFSFLICKGVNKEYLMYSALTRDPFSVIEESLPGGLKEHDFNPEEAEETKQVSWKLVTEYAMETKCDDVLLLLGMYLEFQYSFEMCLKCIKKEQPSHYKYHEKHYANAAIFADSKNQKTICQQAVDTVLAKKRVDSLQLTREQMLTNRFNDLLDRMDIMFGSTGSADIEEWMAGVAWLHCLLPKMDSVVYDFLKCMVYNIPKKRYWLFKGPIDSGKTTLAAALLELCGGKALNVNLPLDRLNFELGVAIDQFLVVFEDVKGTGGESRDLPSGQGINNLDNLRDYLDGSVKVNLEKKHLNKRTQIFPPGIVTMNEYSVPKTLQARFVKQIDFRPKDYLKHCLERSEFLLEKRIIQSGIALLLMLIWYRPVAEFAQSIQSRIVEWKERLDKEFSLSVYQKMKFNVAMGIGVLDWLRNSDDDDEDSQENADKNEDGGEKNMEDSGHETGIDSQSQGSFQAPQSSQSVHDHNQPYHICRGFTCFKKPPTPPPEPET
  
Inhibitor
Name:
BDBM60363
Synonyms:
(4E)-4-[[(5-amino-1-tetrazolyl)amino]methylidene]-2-methoxy-1-cyclohexa-2,5-dienone | (4E)-4-[[(5-aminotetrazol-1-yl)amino]methylene]-2-methoxy-cyclohexa-2,5-dien-1-one | (4E)-4-[[(5-aminotetrazol-1-yl)amino]methylidene]-2-methoxycyclohexa-2,5-dien-1-one | (4E)-4-[[(5-azanyl-1,2,3,4-tetrazol-1-yl)amino]methylidene]-2-methoxy-cyclohexa-2,5-dien-1-one | MLS000081472 | SMR000043300 | cid_5389555
Type:
Small organic molecule
Emp. Form.:
C9H10N6O2
Mol. Mass.:
234.2147
SMILES:
COc1cc(C=Nn2nnnc2N)ccc1O |w:6.6|
Structure:
Search PDB for entries with ligand similarity: