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Target
Large T antigen
Ligand
BDBM51541
Substrate
n/a
Meas. Tech.
Identification of SV40 T antigen inhibitors: A route to novel anti-viral reagents
IC50
7640±n/a nM
Citation
 PubChem, PC Identification of SV40 T antigen inhibitors: A route to novel anti-viral reagents PubChem Bioassay (2010)[AID] 
Target
Name:
Large T antigen
Synonyms:
LT | LT-AG | LT_SV40
Type:
Enzyme Catalytic Domain
Mol. Mass.:
81575.54
Organism:
Simian virus 40
Description:
P03070
Residue:
708
Sequence:
MDKVLNREESLQLMDLLGLERSAWGNIPLMRKAYLKKCKEFHPDKGGDEEKMKKMNTLYKKMEDGVKYAHQPDFGGFWDATEIPTYGTDEWEQWWNAFNEENLFCSEEMPSSDDEATADSQHSTPPKKKRKVEDPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYSVTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLCTFSFLICKGVNKEYLMYSALTRDPFSVIEESLPGGLKEHDFNPEEAEETKQVSWKLVTEYAMETKCDDVLLLLGMYLEFQYSFEMCLKCIKKEQPSHYKYHEKHYANAAIFADSKNQKTICQQAVDTVLAKKRVDSLQLTREQMLTNRFNDLLDRMDIMFGSTGSADIEEWMAGVAWLHCLLPKMDSVVYDFLKCMVYNIPKKRYWLFKGPIDSGKTTLAAALLELCGGKALNVNLPLDRLNFELGVAIDQFLVVFEDVKGTGGESRDLPSGQGINNLDNLRDYLDGSVKVNLEKKHLNKRTQIFPPGIVTMNEYSVPKTLQARFVKQIDFRPKDYLKHCLERSEFLLEKRIIQSGIALLLMLIWYRPVAEFAQSIQSRIVEWKERLDKEFSLSVYQKMKFNVAMGIGVLDWLRNSDDDDEDSQENADKNEDGGEKNMEDSGHETGIDSQSQGSFQAPQSSQSVHDHNQPYHICRGFTCFKKPPTPPPEPET
  
Inhibitor
Name:
BDBM51541
Synonyms:
2-(4-Amino-phenyl)-4-chloro-3H-benzoimidazol-5-ylamine | 2-(4-aminophenyl)-4-chloranyl-1H-benzimidazol-5-amine | 2-(4-aminophenyl)-4-chloro-1H-benzimidazol-5-amine | MLS000084694 | SMR000019041 | [4-(5-amino-4-chloro-1H-benzimidazol-2-yl)phenyl]amine | cid_762544
Type:
Small organic molecule
Emp. Form.:
C13H11ClN4
Mol. Mass.:
258.706
SMILES:
Nc1ccc(cc1)-c1nc2ccc(N)c(Cl)c2[nH]1
Structure:
Search PDB for entries with ligand similarity: