Reaction Details Report a problem with these data
Target
G-protein coupled receptor 55
Ligand
BDBM61475
Substrate
n/a
Meas. Tech.
Image-Based HTS for Selective Antagonists for GPR55
IC50
868.605±n/a nM
Citation
 PubChem, PC Image-Based HTS for Selective Antagonists for GPR55 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 55
Synonyms:
G protein-coupled receptor 55 | GPR55 | GPR55_HUMAN
Type:
PROTEIN
Mol. Mass.:
36649.72
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1292265
Residue:
319
Sequence:
MSQQNTSGDCLFDGVNELMKTLQFAVHIPTFVLGLLLNLLAIHGFSTFLKNRWPDYAATSIYMINLAVFDLLLVLSLPFKMVLSQVQSPFPSLCTLVECLYFVSMYGSVFTICFISMDRFLAIRYPLLVSHLRSPRKIFGICCTIWVLVWTGSIPIYSFHGKVEKYMCFHNMSDDTWSAKVFFPLEVFGFLLPMGIMGFCCSRSIHILLGRRDHTQDWVQQKACIYSIAASLAVFVVSFLPVHLGFFLQFLVRNSFIVECRAKQSISFFLQLSMCFSNVNCCLDVFCYYFVIKEFRMNIRAHRPSRVQLVLQDTTISRG
  
Inhibitor
Name:
BDBM61475
Synonyms:
MLS000579674 | N-(3-aminocarbonyl-4,5-dimethyl-thiophen-2-yl)-2-(3-methylphenyl)quinoline-4-carboxamide | N-(3-carbamoyl-4,5-dimethyl-2-thienyl)-2-(m-tolyl)cinchoninamide | N-(3-carbamoyl-4,5-dimethyl-2-thiophenyl)-2-(3-methylphenyl)-4-quinolinecarboxamide | N-(3-carbamoyl-4,5-dimethylthiophen-2-yl)-2-(3-methylphenyl)quinoline-4-carboxamide | N-[3-(aminocarbonyl)-4,5-dimethyl-2-thienyl]-2-(3-methylphenyl)-4-quinolinecarboxamide | SMR000186862 | cid_1358604
Type:
Small organic molecule
Emp. Form.:
C24H21N3O2S
Mol. Mass.:
415.507
SMILES:
Cc1sc(NC(=O)c2cc(nc3ccccc23)-c2cccc(C)c2)c(C(N)=O)c1C
Structure:
Search PDB for entries with ligand similarity: