Reaction Details Report a problem with these data
Target
G-protein coupled receptor 55
Ligand
BDBM61507
Substrate
n/a
Meas. Tech.
Image-Based HTS for Selective Antagonists for GPR55
IC50
500±n/a nM
Citation
 PubChem, PC Image-Based HTS for Selective Antagonists for GPR55 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 55
Synonyms:
G protein-coupled receptor 55 | GPR55 | GPR55_HUMAN
Type:
PROTEIN
Mol. Mass.:
36649.72
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1292265
Residue:
319
Sequence:
MSQQNTSGDCLFDGVNELMKTLQFAVHIPTFVLGLLLNLLAIHGFSTFLKNRWPDYAATSIYMINLAVFDLLLVLSLPFKMVLSQVQSPFPSLCTLVECLYFVSMYGSVFTICFISMDRFLAIRYPLLVSHLRSPRKIFGICCTIWVLVWTGSIPIYSFHGKVEKYMCFHNMSDDTWSAKVFFPLEVFGFLLPMGIMGFCCSRSIHILLGRRDHTQDWVQQKACIYSIAASLAVFVVSFLPVHLGFFLQFLVRNSFIVECRAKQSISFFLQLSMCFSNVNCCLDVFCYYFVIKEFRMNIRAHRPSRVQLVLQDTTISRG
  
Inhibitor
Name:
BDBM61507
Synonyms:
(Z)-2-(Morpholine-4-carbonyl)-3-[1-phenyl-3-(4-propylsulfanyl-phenyl)-1H-pyrazol-4-yl]-acrylonitrile | (Z)-2-(morpholine-4-carbonyl)-3-[1-phenyl-3-(4-propylsulfanylphenyl)pyrazol-4-yl]prop-2-enenitrile | (Z)-2-(morpholine-4-carbonyl)-3-[1-phenyl-3-[4-(propylthio)phenyl]pyrazol-4-yl]acrylonitrile | (Z)-2-[4-morpholinyl(oxo)methyl]-3-[1-phenyl-3-[4-(propylthio)phenyl]-4-pyrazolyl]-2-propenenitrile | (Z)-2-morpholin-4-ylcarbonyl-3-[1-phenyl-3-(4-propylsulfanylphenyl)pyrazol-4-yl]prop-2-enenitrile | MLS000590161 | SMR000219377 | cid_1874996
Type:
Small organic molecule
Emp. Form.:
C26H26N4O2S
Mol. Mass.:
458.575
SMILES:
CCCSc1ccc(cc1)-c1nn(cc1\C=C(\C#N)C(=O)N1CCOCC1)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: