Reaction Details Report a problem with these data
Target
G-protein coupled receptor 55
Ligand
BDBM57891
Substrate
n/a
Meas. Tech.
Image-Based HTS for Selective Antagonists for GPR55
IC50
500±n/a nM
Citation
 PubChem, PC Image-Based HTS for Selective Antagonists for GPR55 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 55
Synonyms:
G protein-coupled receptor 55 | GPR55 | GPR55_HUMAN
Type:
PROTEIN
Mol. Mass.:
36649.72
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1292265
Residue:
319
Sequence:
MSQQNTSGDCLFDGVNELMKTLQFAVHIPTFVLGLLLNLLAIHGFSTFLKNRWPDYAATSIYMINLAVFDLLLVLSLPFKMVLSQVQSPFPSLCTLVECLYFVSMYGSVFTICFISMDRFLAIRYPLLVSHLRSPRKIFGICCTIWVLVWTGSIPIYSFHGKVEKYMCFHNMSDDTWSAKVFFPLEVFGFLLPMGIMGFCCSRSIHILLGRRDHTQDWVQQKACIYSIAASLAVFVVSFLPVHLGFFLQFLVRNSFIVECRAKQSISFFLQLSMCFSNVNCCLDVFCYYFVIKEFRMNIRAHRPSRVQLVLQDTTISRG
  
Inhibitor
Name:
BDBM57891
Synonyms:
4-[3-[(3-chloro-4-methoxy-phenyl)carbamoyl]-7-keto-1H-pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carboxylic acid tert-butyl ester | 4-[3-[(3-chloro-4-methoxyanilino)-oxomethyl]-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl]-1-piperidinecarboxylic acid tert-butyl ester | MLS000674599 | SMR000314041 | cid_6619478 | tert-butyl 4-(3-{[(3-chloro-4-methoxyphenyl)amino]carbonyl}-7-hydroxypyrazolo[1,5-a]pyrimidin-5-yl)piperidine-1-carboxylate | tert-butyl 4-[3-[(3-chloranyl-4-methoxy-phenyl)carbamoyl]-7-oxidanylidene-1H-pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carboxylate | tert-butyl 4-[3-[(3-chloro-4-methoxyphenyl)carbamoyl]-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carboxylate
Type:
Small organic molecule
Emp. Form.:
C24H28ClN5O5
Mol. Mass.:
501.963
SMILES:
COc1ccc(NC(=O)c2c[nH]n3c2nc(cc3=O)C2CCN(CC2)C(=O)OC(C)(C)C)cc1Cl
Structure:
Search PDB for entries with ligand similarity: