Reaction Details Report a problem with these data
Target
G-protein coupled receptor 35
Ligand
BDBM48749
Substrate
n/a
Meas. Tech.
Image-Based HTS for Selective Antagonists of GPR35
IC50
898.3747±n/a nM
Citation
 PubChem, PC Image-Based HTS for Selective Antagonists of GPR35 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM48749
Synonyms:
(5Z)-5-(2,5-dimethoxy-4-pyrrolidino-benzylidene)-3-ethyl-2-ethylimino-thiazolidin-4-one | (5Z)-5-[(2,5-dimethoxy-4-pyrrolidin-1-yl-phenyl)methylidene]-3-ethyl-2-ethylimino-1,3-thiazolidin-4-one | (5Z)-5-[(2,5-dimethoxy-4-pyrrolidin-1-ylphenyl)methylidene]-3-ethyl-2-ethylimino-1,3-thiazolidin-4-one | (5Z)-5-[[2,5-dimethoxy-4-(1-pyrrolidinyl)phenyl]methylidene]-3-ethyl-2-ethylimino-4-thiazolidinone | 5-[2,5-dimethoxy-4-(1-pyrrolidinyl)benzylidene]-3-ethyl-2-(ethylimino)-1,3-thiazolidin-4-one | MLS000702004 | SMR000228966 | cid_6974996
Type:
Small organic molecule
Emp. Form.:
C20H27N3O3S
Mol. Mass.:
389.512
SMILES:
CC\N=C1\S\C(=C/c2cc(OC)c(cc2OC)N2CCCC2)C(=O)N1CC
Structure:
Search PDB for entries with ligand similarity: