Reaction Details Report a problem with these data
Target
G-protein coupled receptor 35
Ligand
BDBM61627
Substrate
n/a
Meas. Tech.
Image-Based HTS for Selective Antagonists of GPR35
IC50
1158.43±n/a nM
Citation
 PubChem, PC Image-Based HTS for Selective Antagonists of GPR35 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM61627
Synonyms:
(Z)-3-(4-methoxyphenyl)-N-[2-oxidanylidene-2-[2-[(E)-(2-oxidanyl-4-oxidanylidene-cyclohexa-2,5-dien-1-ylidene)methyl]hydrazinyl]ethyl]prop-2-enamide | (Z)-N-[1-(2,4-Dihydroxy-phenyl)-meth-(E)-ylidene-hydrazinocarbonylmethyl]-3-(4-methoxy-phenyl)-acryla mide | (Z)-N-[2-[2-[(E)-(2-hydroxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]hydrazinyl]-2-oxoethyl]-3-(4-methoxyphenyl)prop-2-enamide | (Z)-N-[2-[N'-[(E)-(2-hydroxy-4-keto-cyclohexa-2,5-dien-1-ylidene)methyl]hydrazino]-2-keto-ethyl]-3-(4-methoxyphenyl)acrylamide | (Z)-N-[2-[[(E)-(2-hydroxy-4-oxo-1-cyclohexa-2,5-dienylidene)methyl]hydrazo]-2-oxoethyl]-3-(4-methoxyphenyl)-2-propenamide | MLS000776849 | SMR000413247 | cid_6506792
Type:
Small organic molecule
Emp. Form.:
C19H19N3O5
Mol. Mass.:
369.3713
SMILES:
COc1ccc(C=CC(=O)NCC(=O)NN=Cc2ccc(O)cc2O)cc1 |w:15.14,6.5|
Structure:
Search PDB for entries with ligand similarity: