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Target
G-protein coupled receptor 35
Ligand
BDBM61629
Substrate
n/a
Meas. Tech.
Image-Based HTS for Selective Antagonists of GPR35
IC50
500±n/a nM
Citation
 PubChem, PC Image-Based HTS for Selective Antagonists of GPR35 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM61629
Synonyms:
2-[3-((E)-3-Furan-2-yl-acryloylamino)-benzoylamino]-benzoic acid | 2-[[3-[[(E)-3-(2-furyl)acryloyl]amino]benzoyl]amino]benzoic acid | 2-[[3-[[(E)-3-(furan-2-yl)prop-2-enoyl]amino]benzoyl]amino]benzoic acid | 2-[[3-[[(E)-3-(furan-2-yl)prop-2-enoyl]amino]phenyl]carbonylamino]benzoic acid | 2-[[[3-[[(E)-3-(2-furanyl)-1-oxoprop-2-enyl]amino]phenyl]-oxomethyl]amino]benzoic acid | MLS000807026 | SMR000414840 | cid_1025943
Type:
Small organic molecule
Emp. Form.:
C21H16N2O5
Mol. Mass.:
376.3621
SMILES:
OC(=O)c1ccccc1NC(=O)c1cccc(NC(=O)\C=C\c2ccco2)c1
Structure:
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