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Target
G-protein coupled receptor 35
Ligand
BDBM53032
Substrate
n/a
Meas. Tech.
Image-Based HTS for Selective Antagonists of GPR35
IC50
1122.056±n/a nM
Citation
 PubChem, PC Image-Based HTS for Selective Antagonists of GPR35 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM53032
Synonyms:
(5E)-5-[4-(dimethylamino)benzylidene]-3-methyl-2-thioxo-oxazolidin-4-one | (5E)-5-[[4-(dimethylamino)phenyl]methylidene]-3-methyl-2-sulfanylidene-1,3-oxazolidin-4-one | (5E)-5-[[4-(dimethylamino)phenyl]methylidene]-3-methyl-2-sulfanylidene-4-oxazolidinone | 5-[4-(dimethylamino)benzylidene]-3-methyl-2-thioxo-1,3-oxazolidin-4-one | MLS001008595 | SMR000495844 | cid_2259994
Type:
Small organic molecule
Emp. Form.:
C13H14N2O2S
Mol. Mass.:
262.327
SMILES:
CN(C)c1ccc(\C=C2\OC(=S)N(C)C2=O)cc1
Structure:
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