Reaction Details Report a problem with these data
Target
G-protein coupled receptor 35
Ligand
BDBM61636
Substrate
n/a
Meas. Tech.
Image-Based HTS for Selective Antagonists of GPR35
IC50
2161.021±n/a nM
Citation
 PubChem, PC Image-Based HTS for Selective Antagonists of GPR35 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM61636
Synonyms:
2-[4-[(E)-3-(4-cyclohexylphenyl)-3-keto-prop-1-enyl]phenoxy]acetic acid | 2-[4-[(E)-3-(4-cyclohexylphenyl)-3-oxidanylidene-prop-1-enyl]phenoxy]ethanoic acid | 2-[4-[(E)-3-(4-cyclohexylphenyl)-3-oxoprop-1-enyl]phenoxy]acetic acid | MLS001176722 | SMR000595379 | cid_8108341
Type:
Small organic molecule
Emp. Form.:
C23H24O4
Mol. Mass.:
364.4343
SMILES:
OC(=O)COc1ccc(\C=C\C(=O)c2ccc(cc2)C2CCCCC2)cc1
Structure:
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