Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 1
Ligand
BDBM61778
Substrate
n/a
Meas. Tech.
Fluorescence-based dose response cell-based high-throughput screening assay for agonists of NPY-Y1.
EC50
7050±n/a nM
Citation
 PubChem, PC Fluorescence-based dose response cell-based high-throughput screening assay for agonists of NPY-Y1. PubChem Bioassay (2009)[AID] 
Target
Name:
Neuropeptide Y receptor type 1
Synonyms:
NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44399.07
Organism:
Homo sapiens (Human)
Description:
NPY-Y1 NPY1R HUMAN::P25929
Residue:
384
Sequence:
MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEKI
  
Inhibitor
Name:
BDBM61778
Synonyms:
2-benzyl-3-[4-(diethylamino)anilino]-3-keto-propionic acid ethyl ester | 3-[4-(diethylamino)anilino]-3-oxo-2-(phenylmethyl)propanoic acid ethyl ester | MLS000573081 | SMR000185011 | cid_2836861 | ethyl 2-benzyl-3-[4-(diethylamino)anilino]-3-oxopropanoate | ethyl 2-benzyl-3-{[4-(diethylamino)phenyl]amino}-3-oxopropanoate | ethyl 3-[[4-(diethylamino)phenyl]amino]-3-oxidanylidene-2-(phenylmethyl)propanoate
Type:
Small organic molecule
Emp. Form.:
C22H28N2O3
Mol. Mass.:
368.4693
SMILES:
CCOC(=O)C(Cc1ccccc1)C(=O)Nc1ccc(cc1)N(CC)CC
Structure:
Search PDB for entries with ligand similarity: