Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 1
Ligand
BDBM61848
Substrate
n/a
Meas. Tech.
Fluorescence-based counterscreen for agonists of NPY-Y2: cell-based high-throughput dose response assay for agonists of NPY-Y1.
EC50
24391±n/a nM
Citation
 PubChem, PC Fluorescence-based counterscreen for agonists of NPY-Y2: cell-based high-throughput dose response assay for agonists of NPY-Y1. PubChem Bioassay (2009)[AID] 
Target
Name:
Neuropeptide Y receptor type 1
Synonyms:
NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44399.07
Organism:
Homo sapiens (Human)
Description:
NPY-Y1 NPY1R HUMAN::P25929
Residue:
384
Sequence:
MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEKI
  
Inhibitor
Name:
BDBM61848
Synonyms:
3-(2-amino-5-phenyl-3-thienyl)-4-cyclohexyl-1H-1,2,4-triazole-5-thione | 3-(2-amino-5-phenyl-3-thiophenyl)-4-cyclohexyl-1H-1,2,4-triazole-5-thione | 3-(2-amino-5-phenylthiophen-3-yl)-4-cyclohexyl-1H-1,2,4-triazole-5-thione | 3-(2-azanyl-5-phenyl-thiophen-3-yl)-4-cyclohexyl-1H-1,2,4-triazole-5-thione | 5-(2-amino-5-phenyl-3-thienyl)-4-cyclohexyl-2,4-dihydro-3H-1,2,4-triazole-3-thione | MLS000859724 | SMR000459103 | cid_2816767
Type:
Small organic molecule
Emp. Form.:
C18H20N4S2
Mol. Mass.:
356.508
SMILES:
Nc1sc(cc1-c1n[nH]c(=S)n1C1CCCCC1)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: