Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 1
Ligand
BDBM58233
Substrate
n/a
Meas. Tech.
Fluorescence-based counterscreen for agonists of NPY-Y2: cell-based high-throughput dose response assay for agonists of NPY-Y1.
EC50
33309±n/a nM
Citation
 PubChem, PC Fluorescence-based counterscreen for agonists of NPY-Y2: cell-based high-throughput dose response assay for agonists of NPY-Y1. PubChem Bioassay (2009)[AID] 
Target
Name:
Neuropeptide Y receptor type 1
Synonyms:
NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44399.07
Organism:
Homo sapiens (Human)
Description:
NPY-Y1 NPY1R HUMAN::P25929
Residue:
384
Sequence:
MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEKI
  
Inhibitor
Name:
BDBM58233
Synonyms:
2-amino-2-sulfanylidene-N-[4-(trifluoromethoxy)anilino]ethanimidoyl cyanide | 2-cyano-2-[[4-(trifluoromethoxy)phenyl]hydrazinylidene]ethanethioamide | 2-cyano-2-[[4-(trifluoromethoxy)phenyl]hydrazono]thioacetamide | 2-cyano-2-[[4-(trifluoromethyloxy)phenyl]hydrazinylidene]ethanethioamide | 2-cyano-2-{2-[4-(trifluoromethoxy)phenyl]hydrazono}ethanethioamide | MLS000834858 | SMR000461374 | cid_2744440
Type:
Small organic molecule
Emp. Form.:
C10H7F3N4OS
Mol. Mass.:
288.249
SMILES:
NC(=S)C(=NNc1ccc(OC(F)(F)F)cc1)C#N |w:4.4|
Structure:
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