Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 2
Ligand
BDBM37109
Substrate
n/a
Meas. Tech.
Fluorescence-based counterscreen for agonists of NPY-Y1: cell-based high-throughput dose response assay for agonists of NPY-Y2.
EC50
35430±n/a nM
Citation
 PubChem, PC Fluorescence-based counterscreen for agonists of NPY-Y1: cell-based high-throughput dose response assay for agonists of NPY-Y2. PubChem Bioassay (2009)[AID] 
Target
Name:
Neuropeptide Y receptor type 2
Synonyms:
NPY-Y2 | NPY-Y2 receptor | NPY2-R | NPY2R | NPY2R_HUMAN | Neuropeptide Y receptor type 2 | Y2 receptor | neuropeptide Y receptor Y2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42734.65
Organism:
Homo sapiens (Human)
Description:
NPY-Y2 NPY2R HUMAN::P49146
Residue:
381
Sequence:
MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
  
Inhibitor
Name:
BDBM37109
Synonyms:
MLS000049114 | N-[2-(3-chloranyl-4-methoxy-phenyl)benzotriazol-5-yl]methanesulfonamide | N-[2-(3-chloro-4-methoxy-phenyl)benzotriazol-5-yl]methanesulfonamide | N-[2-(3-chloro-4-methoxyphenyl)-2H-1,2,3-benzotriazol-5-yl]methanesulfonamide | N-[2-(3-chloro-4-methoxyphenyl)-5-benzotriazolyl]methanesulfonamide | N-[2-(3-chloro-4-methoxyphenyl)benzotriazol-5-yl]methanesulfonamide | SMR000074427 | cid_1091853
Type:
Small organic molecule
Emp. Form.:
C14H13ClN4O3S
Mol. Mass.:
352.796
SMILES:
COc1ccc(cc1Cl)-n1nc2ccc(NS(C)(=O)=O)cc2n1
Structure:
Search PDB for entries with ligand similarity: