Reaction Details Report a problem with these data
Target
Neuropeptides B/W receptor type 1
Ligand
BDBM62099
Substrate
n/a
Meas. Tech.
Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7).
IC50
43807±n/a nM
Citation
 PubChem, PC Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7). PubChem Bioassay (2010)[AID] 
Target
Name:
Neuropeptides B/W receptor type 1
Synonyms:
GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36111.82
Organism:
Homo sapiens (Human)
Description:
gi_119607128
Residue:
328
Sequence:
MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
  
Inhibitor
Name:
BDBM62099
Synonyms:
2-[5-amino-4-(4-tert-butylphenyl)sulfonyl-1-triazolyl]-N-(2-methylphenyl)acetamide | 2-[5-amino-4-(4-tert-butylphenyl)sulfonyl-triazol-1-yl]-N-(o-tolyl)acetamide | 2-[5-amino-4-(4-tert-butylphenyl)sulfonyltriazol-1-yl]-N-(2-methylphenyl)acetamide | 2-[5-azanyl-4-(4-tert-butylphenyl)sulfonyl-1,2,3-triazol-1-yl]-N-(2-methylphenyl)ethanamide | 2-{5-amino-4-[(4-tert-butylphenyl)sulfonyl]-1H-1,2,3-triazol-1-yl}-N-(2-methylphenyl)acetamide | MLS000586851 | SMR000208781 | cid_15944698
Type:
Small organic molecule
Emp. Form.:
C21H25N5O3S
Mol. Mass.:
427.52
SMILES:
Cc1ccccc1NC(=O)Cn1nnc(c1N)S(=O)(=O)c1ccc(cc1)C(C)(C)C
Structure:
Search PDB for entries with ligand similarity: