Reaction Details Report a problem with these data
Target
Neuropeptides B/W receptor type 1
Ligand
BDBM62127
Substrate
n/a
Meas. Tech.
Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7).
IC50
12666±n/a nM
Citation
 PubChem, PC Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7). PubChem Bioassay (2010)[AID] 
Target
Name:
Neuropeptides B/W receptor type 1
Synonyms:
GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36111.82
Organism:
Homo sapiens (Human)
Description:
gi_119607128
Residue:
328
Sequence:
MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
  
Inhibitor
Name:
BDBM62127
Synonyms:
2-[4-(2-chlorobenzyl)-2,2-dimethyl-tetrahydropyran-4-yl]ethyl-[1-(2-thienyl)ethyl]amine | MLS000333618 | N-[2-[4-[(2-chlorophenyl)methyl]-2,2-dimethyl-4-oxanyl]ethyl]-1-thiophen-2-ylethanamine | N-[2-[4-[(2-chlorophenyl)methyl]-2,2-dimethyl-oxan-4-yl]ethyl]-1-thiophen-2-yl-ethanamine | N-[2-[4-[(2-chlorophenyl)methyl]-2,2-dimethyloxan-4-yl]ethyl]-1-thiophen-2-ylethanamine | SMR000437781 | cid_3338232 | {2-[4-(2-Chloro-benzyl)-2,2-dimethyl-tetrahydro-pyran-4-yl]-ethyl}-(1-thiophen-2-yl-ethyl)-amine
Type:
Small organic molecule
Emp. Form.:
C22H30ClNOS
Mol. Mass.:
391.998
SMILES:
CC(NCCC1(Cc2ccccc2Cl)CCOC(C)(C)C1)c1cccs1
Structure:
Search PDB for entries with ligand similarity: