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Target
Sphingosine 1-phosphate receptor 4
Ligand
BDBM57378
Substrate
n/a
Meas. Tech.
Late stage fluorescence dose response cell-based screening assay for antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)
IC50
12020±n/a nM
Citation
 PubChem, PC Late stage fluorescence dose response cell-based screening assay for antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4) PubChem Bioassay (2010)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 4
Synonyms:
EDG6 | Endothelial differentiation G-protein coupled receptor 6 | S1P receptor 4 | S1P receptor Edg-6 | S1P4 | S1PR4 | S1PR4_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-6 | Sphingosine-1-phosphate receptor 4 | sphingosine-1-phosphate 4 S1P4
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
41647.39
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
384
Sequence:
MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLVVLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFLREGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLPLLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRPAARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNSAVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDSFRGSRSLSFRMREPLSSISSVRSI
  
Inhibitor
Name:
BDBM57378
Synonyms:
5-(4-chlorophenyl)sulfinyl-N-phenyl-1,2,3-thiadiazole-4-carboxamide | 5-(4-chlorophenyl)sulfinyl-N-phenyl-4-thiadiazolecarboxamide | 5-(4-chlorophenyl)sulfinyl-N-phenyl-thiadiazole-4-carboxamide | 5-(4-chlorophenyl)sulfinyl-N-phenylthiadiazole-4-carboxamide | 5-[(4-chlorophenyl)sulfinyl]-N-phenyl-1,2,3-thiadiazole-4-carboxamide | MLS000326106 | SMR000170268 | cid_1486982
Type:
Small organic molecule
Emp. Form.:
C15H10ClN3O2S2
Mol. Mass.:
363.842
SMILES:
Clc1ccc(cc1)S(=O)c1snnc1C(=O)Nc1ccccc1
Structure:
Search PDB for entries with ligand similarity: