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Target
Kappa-type opioid receptor
Ligand
BDBM54836
Substrate
n/a
Meas. Tech.
SAR analysis of Agonists of the Kappa Opioid Receptor (KOR) using an Image-Based Assay
EC50
>32000±n/a nM
Citation
 PubChem, PC SAR analysis of Agonists of the Kappa Opioid Receptor (KOR) using an Image-Based Assay PubChem Bioassay (2010)[AID] 
Target
Name:
Kappa-type opioid receptor
Synonyms:
K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42648.76
Organism:
Homo sapiens (Human)
Description:
P41145
Residue:
380
Sequence:
MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRVRNTVQDPAYLRDIDGMNKPV
  
Inhibitor
Name:
BDBM54836
Synonyms:
4-[1-[(7-chloro-4-quinolinyl)hydrazo]propylidene]-1-cyclohexa-2,5-dienone | 4-[1-[2-(7-chloranylquinolin-4-yl)hydrazinyl]propylidene]cyclohexa-2,5-dien-1-one | 4-[1-[2-(7-chloroquinolin-4-yl)hydrazinyl]propylidene]cyclohexa-2,5-dien-1-one | 4-[1-[N'-(7-chloro-4-quinolyl)hydrazino]propylidene]cyclohexa-2,5-dien-1-one | MLS001173902 | SMR000590556 | cid_6036600
Type:
Small organic molecule
Emp. Form.:
C18H16ClN3O
Mol. Mass.:
325.792
SMILES:
CCC(N=Nc1ccnc2cc(Cl)ccc12)c1ccc(O)cc1 |w:3.2|
Structure:
Search PDB for entries with ligand similarity: