Reaction Details Report a problem with these data
Target
Epstein-Barr nuclear antigen 1
Ligand
BDBM62444
Substrate
n/a
Meas. Tech.
Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the Epstein-Barr virus nuclear antigen 1 (EBNA-1)
IC50
7234±n/a nM
Citation
 PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the Epstein-Barr virus nuclear antigen 1 (EBNA-1) PubChem Bioassay (2010)[AID] 
Target
Name:
Epstein-Barr nuclear antigen 1
Synonyms:
EBNA-1 protein | EBNA1 | EBNA1_EBVB9 | Epstein-Barr virus protease (EBV Pr)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
56444.81
Organism:
Human herpesvirus 4
Description:
gi_23893623
Residue:
641
Sequence:
MSDEGPGTGPGNGLGEKGDTSGPEGSGGSGPQRRGGDNHGRGRGRGRGRGGGRPGAPGGSGSGPRHRDGVRRPQKRPSCIGCKGTHGGTGAGAGAGGAGAGGAGAGGGAGAGGGAGGAGGAGGAGAGGGAGAGGGAGGAGGAGAGGGAGAGGGAGGAGAGGGAGGAGGAGAGGGAGAGGGAGGAGAGGGAGGAGGAGAGGGAGAGGAGGAGGAGAGGAGAGGGAGGAGGAGAGGAGAGGAGAGGAGAGGAGGAGAGGAGGAGAGGAGGAGAGGGAGGAGAGGGAGGAGAGGAGGAGAGGAGGAGAGGAGGAGAGGGAGAGGAGAGGGGRGRGGSGGRGRGGSGGRGRGGSGGRRGRGRERARGGSRERARGRGRGRGEKRPRSPSSQSSSSGSPPRRPPPGRRPFFHPVGEADYFEYHQEGGPDGEPDVPPGAIEQGPADDPGEGPSTGPRGQGDGGRRKKGGWFGKHRGQGGSNPKFENIAEGLRALLARSHVERTTDEGTWVAGVFVYGGSKTSLYNLRRGTALAIPQCRLTPLSRLPFGMAPGPGPQPGPLRESIVCYFMVFLQTHIFAEVLKDAIKDLVMTKPAPTCNIRVTVCSFDDGVDLPPWFPPMVEGAAAEGDDGDDGDEGGDGDEGEEGQE
  
Inhibitor
Name:
BDBM62444
Synonyms:
2-{N'-[5-(Benzenesulfonylamino-methyl)-furan-2-ylmethylene]-hydrazino}-N-(4-ethoxy-phenyl)-2-oxo-acetamide | MLS000554619 | N'-[[5-(benzenesulfonamidomethyl)-2-furanyl]methylideneamino]-N-(4-ethoxyphenyl)oxamide | N'-[[5-(benzenesulfonamidomethyl)-2-furyl]methyleneamino]-N-p-phenetyl-oxamide | N'-[[5-(benzenesulfonamidomethyl)furan-2-yl]methylideneamino]-N-(4-ethoxyphenyl)oxamide | N-(4-ethoxyphenyl)-N'-[[5-(phenylsulfonylaminomethyl)furan-2-yl]methylideneamino]ethanediamide | SMR000172100 | cid_3139240
Type:
Small organic molecule
Emp. Form.:
C22H22N4O6S
Mol. Mass.:
470.498
SMILES:
CCOc1ccc(NC(=O)C(=O)NN=Cc2ccc(CNS(=O)(=O)c3ccccc3)o2)cc1
Structure:
Search PDB for entries with ligand similarity: