Reaction Details Report a problem with these data
Target
Epstein-Barr nuclear antigen 1
Ligand
BDBM62518
Substrate
n/a
Meas. Tech.
Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the Epstein-Barr virus nuclear antigen 1 (EBNA-1)
IC50
5295±n/a nM
Citation
 PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the Epstein-Barr virus nuclear antigen 1 (EBNA-1) PubChem Bioassay (2010)[AID] 
Target
Name:
Epstein-Barr nuclear antigen 1
Synonyms:
EBNA-1 protein | EBNA1 | EBNA1_EBVB9 | Epstein-Barr virus protease (EBV Pr)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
56444.81
Organism:
Human herpesvirus 4
Description:
gi_23893623
Residue:
641
Sequence:
MSDEGPGTGPGNGLGEKGDTSGPEGSGGSGPQRRGGDNHGRGRGRGRGRGGGRPGAPGGSGSGPRHRDGVRRPQKRPSCIGCKGTHGGTGAGAGAGGAGAGGAGAGGGAGAGGGAGGAGGAGGAGAGGGAGAGGGAGGAGGAGAGGGAGAGGGAGGAGAGGGAGGAGGAGAGGGAGAGGGAGGAGAGGGAGGAGGAGAGGGAGAGGAGGAGGAGAGGAGAGGGAGGAGGAGAGGAGAGGAGAGGAGAGGAGGAGAGGAGGAGAGGAGGAGAGGGAGGAGAGGGAGGAGAGGAGGAGAGGAGGAGAGGAGGAGAGGGAGAGGAGAGGGGRGRGGSGGRGRGGSGGRGRGGSGGRRGRGRERARGGSRERARGRGRGRGEKRPRSPSSQSSSSGSPPRRPPPGRRPFFHPVGEADYFEYHQEGGPDGEPDVPPGAIEQGPADDPGEGPSTGPRGQGDGGRRKKGGWFGKHRGQGGSNPKFENIAEGLRALLARSHVERTTDEGTWVAGVFVYGGSKTSLYNLRRGTALAIPQCRLTPLSRLPFGMAPGPGPQPGPLRESIVCYFMVFLQTHIFAEVLKDAIKDLVMTKPAPTCNIRVTVCSFDDGVDLPPWFPPMVEGAAAEGDDGDDGDEGGDGDEGEEGQE
  
Inhibitor
Name:
BDBM62518
Synonyms:
2-(2-keto-4-methyl-chromen-7-yl)oxy-N-(4-methoxy-3-piperidinosulfonyl-phenyl)acetamide | MLS001140011 | N-(4-methoxy-3-piperidin-1-ylsulfonyl-phenyl)-2-(4-methyl-2-oxidanylidene-chromen-7-yl)oxy-ethanamide | N-(4-methoxy-3-piperidin-1-ylsulfonylphenyl)-2-(4-methyl-2-oxochromen-7-yl)oxyacetamide | N-[4-methoxy-3-(1-piperidinylsulfonyl)phenyl]-2-[(4-methyl-2-oxo-1-benzopyran-7-yl)oxy]acetamide | SMR000706009 | cid_16549413
Type:
Small organic molecule
Emp. Form.:
C24H26N2O7S
Mol. Mass.:
486.537
SMILES:
COc1ccc(NC(=O)COc2ccc3c(C)cc(=O)oc3c2)cc1S(=O)(=O)N1CCCCC1
Structure:
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