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Target
Heat shock factor protein 1
Ligand
BDBM41237
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Confimation HTS to Identify Inhibitors of Heat Shock Factor 1 (HSF1)
EC50
>195000±0 nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Confimation HTS to Identify Inhibitors of Heat Shock Factor 1 (HSF1) PubChem Bioassay (2010)[AID] 
Target
Name:
Heat shock factor protein 1
Synonyms:
HSF1_MOUSE | Hsf1 | Hsf1 protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57208.68
Organism:
Mus musculus
Description:
P38532
Residue:
525
Sequence:
MDLAVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKYFKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVTSVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHAQQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSNSAHSVPKYGRQYSLEHVHGPGPYSAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQEPPSPPHSPRVLEASPGRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTGAQAPALPTPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDLFSPSVTMPDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTGSSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS
  
Inhibitor
Name:
BDBM41237
Synonyms:
MLS000090455 | N-[1-(cyclohexylamino)-2-methyl-1-oxidanylidene-butan-2-yl]pyridine-2-carboxamide | N-[1-(cyclohexylamino)-2-methyl-1-oxobutan-2-yl]-2-pyridinecarboxamide | N-[1-(cyclohexylamino)-2-methyl-1-oxobutan-2-yl]pyridine-2-carboxamide | N-[1-(cyclohexylcarbamoyl)-1-methyl-propyl]picolinamide | N-{1-[(cyclohexylamino)carbonyl]-1-methylpropyl}pyridine-2-carboxamide | SMR000025065 | cid_3238072
Type:
Small organic molecule
Emp. Form.:
C17H25N3O2
Mol. Mass.:
303.3993
SMILES:
CCC(C)(NC(=O)c1ccccn1)C(=O)NC1CCCCC1
Structure:
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