Reaction Details Report a problem with these data
Target
Serine/threonine-protein phosphatase
Ligand
BDBM34573
Substrate
n/a
Meas. Tech.
Luminesence Cell-Based Secondary Assay to Identify Inhibitors of Calcineurin
EC50
180000±n/a nM
Citation
 PubChem, PC Luminesence Cell-Based Secondary Assay to Identify Inhibitors of Calcineurin PubChem Bioassay (2010)[AID] 
Target
Name:
Serine/threonine-protein phosphatase
Synonyms:
calcineurin A1, putative | calmodulin-binding protein 1, putative | serine/threonine-protein phosphatase 2B catalytic subunit A1, putative
Type:
Enzyme Catalytic Domain
Mol. Mass.:
69558.03
Organism:
Candida dubliniensis CD36
Description:
gi_223640082
Residue:
607
Sequence:
MSGNTVQRNTEQINNALNAIQHRRTTTGNDLNHTNQRIISQNSINDKDYTIYITDDGEKYSTVERAVKSVDPPVTFKPKDEQVFLSNGKPNHQFLKQHFIHEGRLHEHQAIQILKQATHLLSKESNLLNVPAPVTICGDVHGQYYDLMKLFEVGGDPATTKYLFLGDYVDRGSFSIECLLYLYSLKINYPDTFWMLRGNHECRHLTEYFTFKNECLHKYSEQLYEECLVSFNALPLAAIMNEQFFCVHGGLSPQLTSLDSLRKLHRFREPPTKGLMCDLLWADPIEEYDEDNIDQEYVTNVVRGCSFAFTYKAACKFLDKTKLLSVIRAHEAQNAGYRMYKRTKTMGFPSLLTMFSAPNYLDSYNNKAAVLKYENNVMNIRQFNASPHPYWLPHFMDVFTWSLPFVGEKVTDMLVSILNVCTEEELDEDLPFSESEIGVATKTTKTTTPVSPVSPKAHPPSTRITSPYKSTKLVESDNNPNTNNDDSEMTLEEKKQALRNKIIAIGKMSRMFQVLREEQENVAHLKELNRGSLPKGSLLHGVDGLKNTINSFEEAKAADRINEALPPSPEDIQRLKQEKNTRIRQQIENQEMSGPVFQRLIRRLSQS
  
Inhibitor
Name:
BDBM34573
Synonyms:
(1-oxidospiro[benzimidazol-1-ium-2,1'-cyclohexane]-5-yl)-phenyl-amine | 1-oxidanidyl-N-phenyl-spiro[benzimidazol-1-ium-2,1'-cyclohexane]-5-amine | 1-oxido-N-phenyl-5-spiro[benzimidazol-1-ium-2,1'-cyclohexane]amine | 1-oxido-N-phenylspiro[benzimidazol-1-ium-2,1'-cyclohexane]-5-amine | MLS000079671 | SMR000035951 | cid_657546
Type:
Small organic molecule
Emp. Form.:
C18H19N3O
Mol. Mass.:
293.363
SMILES:
[O-][N+]1=c2ccc(Nc3ccccc3)cc2=NC11CCCCC1 |c:1,16|
Structure:
Search PDB for entries with ligand similarity: