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Target
Serine/threonine-protein phosphatase
Ligand
BDBM64775
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical high throughput dose response assay for inhibitors of Protein Phosphatase 5 (PP5)
IC50
9990±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay for inhibitors of Protein Phosphatase 5 (PP5) PubChem Bioassay (2010)[AID] 
Target
Name:
Serine/threonine-protein phosphatase
Synonyms:
H0YDU8_HUMAN | PPP5C | PPP5C protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
55092.68
Organism:
Homo sapiens (Human)
Description:
gi_37589898
Residue:
484
Sequence:
MAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVGRPSSGS
  
Inhibitor
Name:
BDBM64775
Synonyms:
5-Amino-4-oxo-3-p-tolyl-3,4-dihydro-thieno[3,4-d]pyridazine-1-carboxylic acid ethyl ester | 5-amino-3-(4-methylphenyl)-4-oxo-1-thieno[3,4-d]pyridazinecarboxylic acid ethyl ester | 5-amino-4-keto-3-(p-tolyl)thieno[3,4-d]pyridazine-1-carboxylic acid ethyl ester | MLS000528230 | SMR000120805 | cid_3153302 | ethyl 5-amino-3-(4-methylphenyl)-4-oxothieno[3,4-d]pyridazine-1-carboxylate | ethyl 5-azanyl-3-(4-methylphenyl)-4-oxidanylidene-thieno[3,4-d]pyridazine-1-carboxylate
Type:
Small organic molecule
Emp. Form.:
C16H15N3O3S
Mol. Mass.:
329.374
SMILES:
CCOC(=O)c1nn(-c2ccc(C)cc2)c(=O)c2c(N)scc12
Structure:
Search PDB for entries with ligand similarity: