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Target
Serine/threonine-protein phosphatase
Ligand
BDBM42221
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical high throughput dose response assay for inhibitors of Protein Phosphatase 5 (PP5)
IC50
26358±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay for inhibitors of Protein Phosphatase 5 (PP5) PubChem Bioassay (2010)[AID] 
Target
Name:
Serine/threonine-protein phosphatase
Synonyms:
H0YDU8_HUMAN | PPP5C | PPP5C protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
55092.68
Organism:
Homo sapiens (Human)
Description:
gi_37589898
Residue:
484
Sequence:
MAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVGRPSSGS
  
Inhibitor
Name:
BDBM42221
Synonyms:
2-({4-[3-(4-hydroxyphenyl)acryloyl]phenyl}amino)-3-(1-piperidinyl)naphthoquinone | 2-[4-[(E)-3-(4-hydroxyphenyl)-1-oxoprop-2-enyl]anilino]-3-(1-piperidinyl)naphthalene-1,4-dione | 2-[4-[(E)-3-(4-hydroxyphenyl)acryloyl]anilino]-3-piperidino-1,4-naphthoquinone | 2-[4-[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]anilino]-3-piperidin-1-ylnaphthalene-1,4-dione | 2-[[4-[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]phenyl]amino]-3-piperidin-1-yl-naphthalene-1,4-dione | MLS000578787 | SMR000186576 | cid_5341375
Type:
Small organic molecule
Emp. Form.:
C30H26N2O4
Mol. Mass.:
478.5384
SMILES:
Oc1ccc(C=CC(=O)c2ccc(NC3=C(N4CCCCC4)C(=O)c4ccccc4C3=O)cc2)cc1 |w:6.6,c:14|
Structure:
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