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Target
Serine/threonine-protein phosphatase
Ligand
BDBM64784
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical high throughput dose response assay for inhibitors of Protein Phosphatase 5 (PP5)
IC50
5717±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay for inhibitors of Protein Phosphatase 5 (PP5) PubChem Bioassay (2010)[AID] 
Target
Name:
Serine/threonine-protein phosphatase
Synonyms:
H0YDU8_HUMAN | PPP5C | PPP5C protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
55092.68
Organism:
Homo sapiens (Human)
Description:
gi_37589898
Residue:
484
Sequence:
MAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVGRPSSGS
  
Inhibitor
Name:
BDBM64784
Synonyms:
(4E)-4-[[2-(2,6-dimorpholin-4-ylpyrimidin-4-yl)hydrazinyl]methylidene]-3-hydroxycyclohexa-2,5-dien-1-one | (4E)-4-[[2-(2,6-dimorpholin-4-ylpyrimidin-4-yl)hydrazinyl]methylidene]-3-oxidanyl-cyclohexa-2,5-dien-1-one | (4E)-4-[[N'-(2,6-dimorpholinopyrimidin-4-yl)hydrazino]methylene]-3-hydroxy-cyclohexa-2,5-dien-1-one | (4E)-4-[[[2,6-bis(4-morpholinyl)-4-pyrimidinyl]hydrazo]methylidene]-3-hydroxy-1-cyclohexa-2,5-dienone | 4-[(2,6-Di-morpholin-4-yl-pyrimidin-4-yl)-hydrazonomethyl]-benzene-1,3-diol | MLS000553546 | SMR000171512 | cid_6614507
Type:
Small organic molecule
Emp. Form.:
C19H24N6O4
Mol. Mass.:
400.4317
SMILES:
Oc1ccc(CN=Nc2cc(nc(n2)N2CCOCC2)N2CCOCC2)c(O)c1 |w:7.7|
Structure:
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