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Target
Serine/threonine-protein phosphatase
Ligand
BDBM34768
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical high throughput dose response assay for inhibitors of Protein Phosphatase 5 (PP5)
IC50
4015±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay for inhibitors of Protein Phosphatase 5 (PP5) PubChem Bioassay (2010)[AID] 
Target
Name:
Serine/threonine-protein phosphatase
Synonyms:
H0YDU8_HUMAN | PPP5C | PPP5C protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
55092.68
Organism:
Homo sapiens (Human)
Description:
gi_37589898
Residue:
484
Sequence:
MAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVGRPSSGS
  
Inhibitor
Name:
BDBM34768
Synonyms:
6-N-[(4-methoxyphenyl)methylideneamino]-2-N,2-N,4-N,4-N-tetramethylpyrimidine-2,4,6-triamine | 6-[N'-(4-Methoxy-benzylidene)-hydrazino]-N*2*,N*2*,N*4*,N*4*-tetramethyl-pyrimidine-2,4-diamine | MLS000566872 | N6-[(4-methoxyphenyl)methylideneamino]-N2,N2,N4,N4-tetramethyl-pyrimidine-2,4,6-triamine | N6-[(4-methoxyphenyl)methylideneamino]-N2,N2,N4,N4-tetramethylpyrimidine-2,4,6-triamine | SMR000175280 | [2-(dimethylamino)-6-(N'-p-anisylidenehydrazino)pyrimidin-4-yl]-dimethyl-amine | cid_2850301
Type:
Small organic molecule
Emp. Form.:
C16H22N6O
Mol. Mass.:
314.3855
SMILES:
COc1ccc(CN=Nc2cc(nc(n2)N(C)C)N(C)C)cc1 |w:8.8|
Structure:
Search PDB for entries with ligand similarity: