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Target
Serine/threonine-protein phosphatase
Ligand
BDBM46589
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical high throughput dose response assay for inhibitors of Protein Phosphatase 5 (PP5)
IC50
7450±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay for inhibitors of Protein Phosphatase 5 (PP5) PubChem Bioassay (2010)[AID] 
Target
Name:
Serine/threonine-protein phosphatase
Synonyms:
H0YDU8_HUMAN | PPP5C | PPP5C protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
55092.68
Organism:
Homo sapiens (Human)
Description:
gi_37589898
Residue:
484
Sequence:
MAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVGRPSSGS
  
Inhibitor
Name:
BDBM46589
Synonyms:
2-[(1,8-diamino-5-cyano-6-piperidin-1-yl-2,7-naphthyridin-3-yl)sulfanyl]acetic acid | 2-[(1,8-diamino-5-cyano-6-piperidino-2,7-naphthyridin-3-yl)thio]acetic acid | 2-[[1,8-bis(azanyl)-5-cyano-6-piperidin-1-yl-2,7-naphthyridin-3-yl]sulfanyl]ethanoic acid | 2-[[1,8-diamino-5-cyano-6-(1-piperidinyl)-2,7-naphthyridin-3-yl]thio]acetic acid | MLS000773334 | SMR000364051 | cid_3327739
Type:
Small organic molecule
Emp. Form.:
C16H18N6O2S
Mol. Mass.:
358.418
SMILES:
Nc1nc(SCC(O)=O)cc2c(C#N)c(nc(N)c12)N1CCCCC1
Structure:
Search PDB for entries with ligand similarity: